You can view a list of the awarded projects since 1986 here. This breadth of topics and efforts also reflects the diverse interests of Joslin's diabetes research program as a whole. The approaches have also been very diverse, covering wide varieties of biochemical, molecular biologic, genetic, immunological and clinical strategies. Projects funded in past years have covered a wide range of topics in the fields of type 1 and type 2 diabetes and their complications, including the control of insulin gene expression, mechanisms of insulin action and resistance, stem cell biology, beta-cell apoptosis, and potential regeneration, mechanisms of leptin action and resistance and autoantigen therapy of type 1 diabetes. Kulkarni, MD, PhD, Associate Director of the DRC. During their wait, this group was offered usual care.The Joslin Diabetes Center DRC P&F Grant Program has been providing initial funding for new and innovative research projects for more than 30 years. The delayed start group began 4 weeks later. The immediate arm began at the next available class. To allow for controlled analysis, on presentation at each site, participants were randomly assigned to one of two cohorts: 1) immediate start (A) and 2) delayed start (B). Candidates were excluded if they were < 21 years old and could not give informed consent. Candidates were included if they had type 1 diabetes and used a continuous glucose monitor. Recruitment: Recruitment occurred through the Dartmouth-Hitchcock Medical Center (DHMC) endocrinology clinic and the endocrinologists working there. This was done both as a means of testing delivering this service in a rural setting where patient might be geographically distant or isolated and to accommodate the need for social distancing during the COVID-19 pandemic. In this study's case it was delivered via a videoconferencing platform. It is an 8 session program, typically run in a live group setting. It is designed to cultivate both the early recognition of stress in the mind and body, develop skills to mitigate stress and evoke the relaxation response and cultivate resiliency. Intervention: The Stress Management and Resiliency Training (SMART) program () is well validated comprehensive stress management program. All participants provided written informed consent.
Hypothesis: It was hypothesized that the course on videoconferencing platform would deliver similar effects on quality of life as has been seen in the past from on-site courses, and that the intervention would reduce glucose variability and improve resiliency Design: This pilot was designed as a prospective cohort pre-post intervention study with subjects randomized to an immediate start or wait time control The study was approved by the Committee for the Protection of Human Subjects at Dartmouth Hitchcock Medical Center and Dartmouth College. Condition or diseaseĭiabetes Mellitus Stress, Psychological Stress, Physiologicalīehavioral: Stress Management and Resiliency Training (SMART) program The primary outcome measures were: Glucose variability, the Diabetes Self-Management questionnaire (DSMQ) and the Connor-Davidson Resiliency (CD-RISC) instrument. The intervention was the Stress Management and Resiliency Training (SMART) program conducted over 8 sessions over web-based video conference software. Participants were adult type 1 diabetes patients who used a continuous glucose monitor and recruited from an academic endocrinology practice. The study was designed as a randomized prospective cohort pre-post study with wait time control. Managing stress and cultivating resiliency should improve diabetes management and reduce glucose variability. Continuous glucose monitors allow us to track glucose variability in the real-world environment. Stress physiology influences glucose metabolism. Why Should I Register and Submit Results?.
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